Psychological burden in spinal muscular atrophy patients and their families: a systematic review

Abstract Background Spinal muscular atrophy (SMA) is an autosomal-recessive disorder that manifests in paralysis and skeletal muscle weaknesses. This neuromuscular problem caused by degeneration of the spinal cord anterior horn cells. Main body abstract SMA leads to a decreased motoric function affects patients’ daily activity eventually induces psychological burden. Given increasing burden patients their families, this review summarizes studies assessing families. We aimed highlight leading causes systematically searched literature from period 2011 2020 two electronic databases using keywords “Spinal Muscular Atrophy”, “Psychology”, “Caregivers”, “Burden”, then filtered it with eligibility criteria screened studies. By searching, screening, filtering studies, we included seven review. showed patients, moreover for parents. The dependency mainly since they eagerly struggle achieve everyday life. Conclusion Health professionals’ understanding capability regarding mental condition families potential aspect can create better care. encouraging researchers clinicians have enormous SMA.